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Effect of oligochitosan and oligo-β-glucan supplementation on growth of striped catfish

Posted by:bozhihuili    Published:2016-06-08 14:34

Biotechnol Appl Biochem. 2016 Jun 1. doi: 10.1002/bab.1513. 

Effect of oligochitosan and oligo-β-glucan supplementation on growth, innate immunity 
and disease resistance of striped catfish (Pangasianodon hypophthalmus).

Duy NN1, Van Phu D1, Quoc LA1, Lan NT1, Hai PD2, Van Nguyen N2, Hien NQ1.Author information


Oligochitosan (COS) and oligo-β-glucan (βOG) were prepared by gamma Co-60 irradiation of 
chitosan/H2 O2 and β-glucan/H2 O2 solutions. The striped catfish (P. hypophthalmus) was 
fed by diets containing 0 - 200 mg COS, βOG and mixture of COS/βOG per kg feed for 45 days, 
and then challenged with Edwardsiella ictaluri bacterium. The effects of supplemented COS, βOG 
and mixture of COS/βOG on immune stimulation and growth performance in striped catfish were 
investigated. The results indicated that striped catfish fed with 100 - 200 mg COS or βOG/kg feed, 
the growth performance was significantly improved and the mortality was considerably decreased. 
Furthermore, striped catfish fed with supplementation of 50 mg COS + 50 mg βOG/kg feed was 
the best for increasing weight gain (∼26%) and for decreasing mortality (∼38%) compared with 
control group. Moreover, phagocytic activity and lysozyme activity of fish were enhanced by feeding 
diet supplemented COS and/or βOG. Thus, COS and/or βOG can be potentially utilized as the 
immunostimulants and growth promoters for aquaculture. This article is protected by copyright. 
All rights reserved. This article is protected by copyright. All rights reserved.


Catfish; Growth; Immunostimulant; Oligo-β-glucan; Oligochitosan

PMID: 27245476 [PubMed - as supplied by publisher]


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