Young animals are the most used stage of antibiotics. Feeding antibiotics as growth promoters has a good effect on relieving early weaning stress of piglets. Therefore, finding effective alternatives to feed antibiotics has become a current research focus. Lactobacillus can adhere to and colonize the surface of animal intestinal mucosa, and has a regulatory effect on the host intestinal mucosal immune system, thereby improving the intestinal health of piglets. Chitosan oligosaccharide is an oligosaccharide composed of 2-10 glucosamine linked by β-1,4-glycosidic bonds. It has good water solubility and can improve the growth performance of weaned piglets, improve serum antioxidant indicators, and increase the number of beneficial bacteria. By studying the effects of chitosan oligosaccharide and Lactobacillus casei on the growth performance of weaned piglets, the activity of antioxidant enzymes in serum and the structure of intestinal microflora, the aim is to provide theoretical support for the scientific compatibility of probiotics and prebiotics in livestock and poultry feeds .
In the experiment, 312 30-day-old weaned piglets weighing (7.06±0.02) kg Du × Chang × Da ternary cross were randomly divided into 4 treatment groups, each treatment group was set up with 6 replicates, and each replicate was 13 pigs. The control group (A) was fed a corn-soybean meal basal diet, the experimental group (B) was fed with 0.5 g of chitosan oligosaccharide per kilogram of feed, the experimental group (C) was fed with 1010 CFU of Lactobacillus casei per kilogram of feed, and the experimental group (D) Chitooligosaccharide and Lactobacillus casei were added at the same time, and the test period was 32 days.
The result shows: Group D has the effect of increasing the average daily weight gain and reducing the feed-to-weight ratio of weaned piglets in the three stages of 0-14, 15-32 d and 0-32 d. On the 14th day of the experiment, butyric acid bacillus furinii and Lactobacillus crispatus were significantly increased in groups C and D compared with groups A and B. On the 32nd day of test, group B significantly increased the content of glutathione peroxidase in serum and decreased the content of malondialdehyde (MDA). Group C reduced the diarrhea rate in weaned piglets. Chitooligosaccharide as a feed additive can improve the antioxidant capacity of weaned piglets; lactic acid bacteria can increase the number of intestinal probiotics and reduce the diarrhea rate of weaned piglets; at the same time, adding chitosan oligosaccharide and lactic acid bacteria can effectively improve the feed conversion rate of weaned piglets and improve the intestinal tract. Beneficial microbial population for healthier guts of piglets.
BZ Oligo mainly offer marine oligosaccharide standards and ingredients, containing alginate oligosaccharide, chitosan oligosaccharide, agar oligosaccharide and carrageenan oligosaccharide, which give business opportunities using these untapped oligosaccharides for biological applications targeting lab research, pharmacy, dietary supplement, sustainable agriculture and animal health.
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