Increase neurotransmitters: People with Alzheimer’s have a shortage of some important chemicals in their brain. These chemicals are involved with the transmission of messages within the brain.
Reduce plaques: During the course of AD, protein ‘plaques’ and ‘tangles’ develop in the structure of the brain, leading to the death of brain cells.
Neurons are the chief cells destroyed by Alzheimer's disease.
In the brain, neurons connect and communicate at synapses, where tiny bursts of chemicals called neurotransmitters carry information from one cell to another.
Alzheimer's disrupts this process, and eventually destroys synapses and kills neurons, damaging the brain's communication network. People with Alzheimer’s have been shown to have a shortage of the chemical acetylcholine in their brains.
The 2011 new criteria and guidelines of AD's diagnosing identify two biomarker categories:
(1) Biomarkers showing the level of beta-amyloid accumulation (called amyloid plaques) in the brain.
(2) Biomarkers showing that neurons in the brain are injured or actually degenerating.
The amyloid plaques are believed to interfere with the neuron-to-neuron communication at synapses and to contribute to cell death
Alginate Oligosaccharide can conbine with beta-amyloid (Aβ)，then inhabit the formation of Aβ fibril, stimulate the depolymerization of fibrous Aβ, and reduce the toxicity of Aβ fibril
Alginate Oligosaccharide conbines with Aβ and interact.